Quantification of multiple tumor clones using gene array and sequencing data
نویسندگان
چکیده
منابع مشابه
Quantification of Multiple Tumor Clones Using Gene Array and Sequencing Data.
Cancer development is driven by genomic alterations, including copy number aberrations. The detection of copy number aberrations in tumor cells is often complicated by possible contamination of normal stromal cells in tumor samples and intratumor heterogeneity, namely the presence of multiple clones of tumor cells. In order to correctly quantify copy number aberrations, it is critical to succes...
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ژورنال
عنوان ژورنال: The Annals of Applied Statistics
سال: 2017
ISSN: 1932-6157
DOI: 10.1214/17-aoas1026